Exploring the Future of Healthcare Innovation

In this episode, we speak with Anand Iyer, Chief AI Officer at Welldoc and former wireless technology strategist, about using AI to transform chronic disease management between doctor visits. Anand explains how BlueStar, Welldoc's FDA-regulated cardio-metabolic platform, provides precision coaching to patients while delivering clinical decision support that helps physicians overcome clinical inertia, achieving A1C reductions four times greater than some medications. We discuss the platform's evolution from rules-based AI to Generative AI, the "learned intermediary" philosophy that keeps humans in control, and how Welldoc shifted from prescription-only to an over the counter SaaS model serving millions across health plans and hospital systems.

In this episode, we speak with Demetri Giannikopoulos, Chief Innovation Officer at Rad AI, about transforming radiology workflows with AI-powered documentation. He explains who Rad AI’s cloud-native platform automates impression generation in each radiologist’s unique voice while saving an hour per shift and reducing addendums by 10-15%. With 30% of US radiologists already using their platform and partnerships with leading academic centers, Rad AI is deploying their Series C funding to build AI agents for longitudinal patient management and integrate vision-based foundation models that deliver actionable insights directly into workflows.

In this episode, we speak with Mathai Mammen, the CEO of Parabilis, and a former R&D leader at J&J and Merck, about drugging the previously undruggable 80% of disease-causing proteins inside cells. He explains how the Helicon platform uses AI and unnatural amino acids to create peptides that access intracellular targets unreachable by other drugs. We discuss their lead program’s remarkable clinical results in desmoid tumors, their pipeline in prostate cancer, and why now is the perfect time for innovators to aim high and do something revolutionary in healthcare.

We recently got back from HLTH 2025 in Las Vegas, and it was an incredible experience. The event truly felt like Coachella for medicine. We had the chance to connect with innovators building at the intersection of healthcare and technology, strengthen relationships with physicians driving health tech forward, record content with more than a dozen companies, and even meet Mark Cuban. We also took some time to reflect on how far the podcast has come over the past year and what we’re most excited about as the platform continues to grow.